"Hydroxychloroquine Inneffective in Preventing COVID-19"
Ok, thanks. But it was never intended to prevent Covid-19. It's not a vaccine. It treats symptoms and anecdotal evidence suggests it reduces recovery times.
This study was on post-exposure prophylaxis. Prophylaxis is something that some people have said HCQ is good for. This is another piece of evidence that it's probably not.
However, this study did not shed light on whether HCQ or some sort of HCQ cocktail could ease symptoms, reduce viral load or help lower death rates. There was no viral load measurements in this study (it was done remotely and most of the participants never even got tested).
There were zero deaths of any participants in the study (control of HCQ group) and virtually no hospitalizations.
It was as good a study as they could have done under the circumstances considering logistical constraints they were under in March, and it's a useful data point that HCQ likely has no significant effect of post-exposure prophylaxis, but it did not answer or purport to answer the more important questions (which are still being tested). Dr. Boulware conceded all of this on Twitter. They did another study on early treatment, but the results aren't ready yet. They're also now starting on a pre-exposure prophylaxis study.
Incidentally, the study also showed no serious side effects in the HCQ group, further challenging the conclusion of the now-disgraced Lancet study released 2 weeks ago.
I was disappointed by the results of this study, but in retrospect, it's hard to imagine how HCQ, which use is based on a theory of being used as an anti-inflammatory and/or as a zinc ionophore, ever had a realistic chance of being a useful COVID prophylactic.