The Nimzovich Defence with 2.d4 arises after 1.e4 Nc6 2.d4. ECO code: B00.
White occupies the centre immediately. This is the most testing response to the Nimzovich Defence, establishing a two-pawn centre. Black's main options are 2...e5 (challenging the centre), 2...d5 (entering Scandinavian-like territory), or 2...d6 (the solid approach).