The Poisoned Pawn Variation is a specific line in the Najdorf Variation of the Sicilian Defence: 1.e4 c5 2.Nf3 d6 3.d4 cxd4 4.Nxd4 Nf6 5.Nc3 a6 6.Bg5 e6 7.f4 Qb6, where Black captures the b2-pawn. Bobby Fischer and Garry Kasparov both played this variation extensively.