Safer & more targeted CRISPR gene therapy
12 Nov '20 16:246 editshttps://phys.org/news/2020-11-safer-crispr-gene-therapy.html
they talk about it being used to target cancer, which is interesting. But I see no reason why this couldn't also be used, and via using X-rays rather than light to activate the liposomes, to selectively target, and selectively so to reduce the risk of severe side effects, just one single particular organ of the body that is badly effected by a mutation which functionally only badly effects that particular organ.
For example; If someone has a harmful mutation that only significantly effects liver function and not other organs, this therapy could be used to relatively selectively correct the gene defect in just the liver. Although the X-rays would inadvertently shine through much of the tissue in front and behind the liver and thus that tissue would also be effected, most other tissue of the body won't be so and thus that still would help to reduce the risk of severe side effects.
they talk about it being used to target cancer, which is interesting. But I see no reason why this couldn't also be used, and via using X-rays rather than light to activate the liposomes, to selectively target, and selectively so to reduce the risk of severe side effects, just one single particular organ of the body that is badly effected by a mutation which functionally only badly effects that particular organ.
For example; If someone has a harmful mutation that only significantly effects liver function and not other organs, this therapy could be used to relatively selectively correct the gene defect in just the liver. Although the X-rays would inadvertently shine through much of the tissue in front and behind the liver and thus that tissue would also be effected, most other tissue of the body won't be so and thus that still would help to reduce the risk of severe side effects.