In terms of his notable accomplishments, Sergei Iskusnyh has competed in several important tournaments. He played at the 2008 World Youth Chess Championships, winning the under-16 category. Sergei also played at the 2017 European Individual Championship and at the Russian Chess Championship Higher League in 2016, 2017, 2018 and 2021.
Although he has not won any major world championship or Olympics titles, he is recognized as a significant player within the Russian chess community and the broader international chess community.