@metal-brain saidI listened to two hours of this Dr Robert Malone on Rumble. Two hours I will never get back again. His claim of being the inventor of mRNA vaccines is a little precious.
Prove one single thing he is wrong about.
https://healthfeedback.org/claimreview/[WORD TOO LONG]/
Key Takeaway Like many technologies, the development of the mRNA vaccines was a collaborative effort that spanned a number of research institutes, three decades of work, and hundreds of researchers. Robert Malone contributed to the early development of this vaccine technology, however he is not the sole inventor of mRNA vaccines.
Malone and his co-authors “sparked for the first time the hope that mRNA could have potential as a new drug class”, but that “the achievement of the mRNA vaccines of today is the accomplishment of a lot of collaborative efforts”.
However
a number of different discoveries were necessary to transform the hope of mRNA as a new drug class into mRNA vaccines. For instance, one hurdle was how to cloak mRNA from the immune system, which can detect “foreign” mRNA. In 2004, Katalin Karikó, Drew Weissman and colleagues discovered that one of the synthetic nucleosides–the four building blocks of mRNA–was serving as a big “here I am” signal to the immune system. By swapping that nucleoside for a modified one, the team managed to cloak mRNA from detection. Other modifications made to the mRNA, such as modifying the ends of the mRNA strands, further optimized both the stability and translation of mRNA[1].
only half way there
Another hurdle was how to get mRNA into cells so that proteins can be produced and generate protective immunity. Research for a delivery system turned to nanoparticles, specifically lipid nanoparticles. As an editorial in Nature Reviews Materials mentioned, optimizing lipid nanoparticles to deliver nucleic acids like mRNA was a long road. An extensive history of the process to refine lipid nanoparticles can be found on Chemical & Engineering News.
Which brings us to this sober conclusion
As Karikó told Penn Today, “science builds on science”. The development of the mRNA COVID-19 vaccines (and any future mRNA vaccines) was built on the work of countless researchers. Among these is Malone, who together with his co-authors contributed early evidence that mRNA could be successfully delivered to and expressed in cells. Following a fact-check by Logically Malone admitted that he did not invent the mRNA vaccines, but instead the “vaccine technology platform”. While he contributed to this field when it emerged, Malone is not the “inventor” of the mRNA vaccines, but one of the hundreds of researchers that contributed to their current success.
The Logically article can be found here.
https://www.logically.ai/factchecks/library/3aa2eefd
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@kmax87 saidHe contributed.
I listened to two hours of this Dr Robert Malone on Rumble. Two hours I will never get back again. His claim of being the inventor of mRNA vaccines is a little precious.
https://healthfeedback.org/claimreview/[WORD TOO LONG]/
[quote]Key Takeaway ...[text shortened]... e Logically article can be found here.
https://www.logically.ai/factchecks/library/3aa2eefd
I think that makes him qualified.
Since you watched it can you prove anything he said wrong?
@Metal-Brain
You keep wanting to ignore the part where he said he INVENTED the vaccine.
THAT ruins anything else he did in that field.
@metal-brain saidYes he contributed, but after laying the groundwork for the potential of this class of treatments, he balked at the challenges this new approach presented, leaving the heavy lifting to other researchers who had to find ways to deliver the mRNA into the body without the body's immune response neutralising its benefits. So not one to let the moss grow under his feet, Dr Malone moved on with an advisory chair here and an adjunct professorship there and by 2016 almost 30 years later, as the CEO of his own company, Atheric Pharma, he was contracted by the US Medical Research Institute to assist in developing treatments for the Zika virus by evaluating the efficacy of existing drugs. By 2020 as Chief Medical Officer at Alchem Labs in Florida he advanced the idea of using famotidine and hydroxychloroquine in the treatment of Covid 19.
He contributed.
I think that makes him qualified.
Since you watched it can you prove anything he said wrong?
However when Alchem and Northwest Health of New York engaged in a clinical trial of these two off shelf medications, after promising initial results, Malone resigned shortly after the trial began and Northwell paused the trial due to a shortage of hospitalised patients.
Here's my 2 cents. Dr Malone is a very smart man but missed out on a golden payday because he didn't stick around to solve all the issues that sprang from the potential the mRNA technology envisioned possible. He jumped horses when the horse he was on looked too much of a long shot and when it became apparent that the horse he was on had died, he resigned from Alchem because he was smart enough to realise the futility of flogging it any further.
Would that push you over the edge to launch a disgruntled polemic against the science establishment because after 40 years of hard work you finally lucked out? There's no way of proving that for certain, but it would sure seem so.
@sonhouse saidExactly. Why invest any more time in the testimony of a person who is cavalier about mixing fact and fiction.
@Metal-Brain
You keep wanting to ignore the part where he said he INVENTED the vaccine.
THAT ruins anything else he did in that field.
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@metal-brain saidNo no he didn't.
He invented mRNA Vaccine Technology.
I suppose you think he is not qualified to have an opinion about what he invented.
You are a real piece of work. Should we ignore all the experts? Why stop with him?
As a grad student in the 80s he published 2 papers on what happens after direct injection of genetic material and then dropped out. Those who continued his work were the ones who discovered the immunogenic properties of mRNA. He seems bitter that they've profited on it.
The fact we have been studying this type of vaccine since the early 90s kinda trows a wrench in the gears of the "new technology" crowd.
@sonhouse saidWhere did he say he said he INVENTED the vaccine? He never said that.
@Metal-Brain
You keep wanting to ignore the part where he said he INVENTED the vaccine.
THAT ruins anything else he did in that field.
@wildgrass saidWhat is your source of information?
No no he didn't.
As a grad student in the 80s he published 2 papers on what happens after direct injection of genetic material and then dropped out. Those who continued his work were the ones who discovered the immunogenic properties of mRNA. He seems bitter that they've profited on it.
The fact we have been studying this type of vaccine since the early 90s kinda trows a wrench in the gears of the "new technology" crowd.
@sonhouse saidNo. I agree.
@Metal-Brain
So NATURALLY you disagree since you know better than ANY scientist.
@sonhouse saidI don't know if they did or not. I doubt they did, but the data from Israel simply doesn't support it. If they said why they probably said the data didn't support it because it doesn't.
@Metal-Brain
Did they say WHY they made the decision?
Dr, Malone has been working on vaccines for most of his life.
None of you can call him an anti-vaxxer. That must pain those that want to slander him. They cannot use their favorite misleading pejorative when someone tells the truth they don't like.
The gene vaccines are leaky. That means people who take the gene vaccine can still get the virus and spread it. Those people are hugging other people again. They are loving other people to death.