Originally posted by sonhouse
Telomeres are like the little plastic stuff at the end of your shoelace. It keeps it from unraveling, so when they are duplicated, everything gets duped between telomeres. It also acts a bit like a clock because every now and then, a bit of the telemere goes bye bye, eventually leading to poor reproduction of the gene and may be a cause of aging, among othe ...[text shortened]... hand in it or not, would know humans are not the end of all evolutionary trends, nor the best.
1. The plastic things on the ends of shoes are called
aglets, just fyi.
2. I hate the telomere/aglet analogy although it is far to famous. They prevent the ends of chromosomes from being degraded by various enzymes and provide some protection against other damage to the end of the strand (where it is vunerable), and they keep chromosome ends from getting stuck together or from having other bits of DNA in the cell stuck to them. But I think people overdo the aglet metaphor.
3. A bit of telomere isn't lost "every now and then", every time a cell which does not express telomerase, which I was leaving out of this for simplicity, replicates it's chromosomes, some of the DNA on the ends is lost, this is the important function of telomeres in aging and is what I was talking about.
4. What do you even mean "everything gets duped between the telomeres"?
5.Genes do not all have telomeres on the ends, chromosomes do.
6.Loss of telomeres doesn't lead to "poor reproduction", it leads to outright information loss, genetic material is "deleted" from the ends from one copy of the chromosome to the next. This doesn't poorly reproduce, it isn't copied at all because it isn't there anymore. THIS IS VERY BAD, in fact it is fatal to the cell.
7. I wasn't trying to turn it into a discussion of telomeres, but it was a piece of evidence offered.
8.Evolution has no goals, there isn't a 'next stage', just a future and a past. True we aren't the end of all evolutionary processes, but anything that comes after us will not neccesarily be better or worse. There is no long term plan or goal to evolution, it is just about sex and babies, who can have the most and have them survive.
9.God created man in his image, or so I am told. Maybe God is too egocentric to care about other animals, that is why they aren't allowed in heaven.